RAD-150

Description

RAD-150, also referred to as TLB-150 and marketed by vendors as “Test 2.0,” is a synthetic nonsteroidal androgen receptor modulator (SARM)-related research compound. It has been developed as a structural analogue of RAD-140 (Testolone). RAD-150 is frequently described as a next-generation analogue of RAD-140. RAD-150 has been investigated for its interaction with the androgen receptor (AR), a nuclear hormone receptor involved in regulating gene expression associated with skeletal muscle, bone, and reproductive tissues. However, the precise receptor binding characteristics, tissue selectivity, pharmacokinetics, and downstream signaling mechanisms of RAD-150 have not been fully characterized. Research involving selective androgen receptor modulators aims to understand tissue-selective androgen receptor activation while minimizing the effects traditionally associated with anabolic androgenic steroids.

Product Specifications

• Compound / Peptide Name: RAD-150
• Classification: Synthetic nonsteroidal androgen receptor modulator (investigational)
• Sequence: Not applicable
• Molecular Formula: C₁₆H₂₅ClN₂O
• Molecular Weight: Not available in the provided information
• CAS Number: Not available in public databases
• Form: Tablets
• Strength: 10 mg/tablet
• Purity: 99% (manufacturer specification)
• Solubility: Research-dependent
• Regulatory Status: Investigational research compound; not approved for human therapeutic use by major regulatory authorities

What Is It Used For and Its Purpose 

RAD-150 is supplied as a laboratory research compound for investigations involving androgen receptor biology. Research interest centers on understanding how SARMs influence receptor-mediated gene expression, anabolic signaling, and tissue-selective pharmacology. Investigators studying SARMs seek to better understand androgen receptor activation in skeletal muscle, bone, and other androgen-responsive tissues while evaluating differences from traditional anabolic steroids.

Research Applications

• Androgen receptor biology
• Nuclear receptor signaling
• Skeletal muscle biology
• Bone biology
• Gene regulation
• Pharmacology
• Medicinal chemistry
• Structure–activity relationship (SAR) research
• Drug discovery

Potential Scientific Benefits 

Theoretical interest in RAD-150 is based on its structural relationship to RAD-140 and the broader class of selective androgen receptor modulators. Compounds within this class are investigated for their ability to selectively activate androgen receptor signaling in specific tissues while minimizing activity in others. Current research interest focuses on understanding receptor-mediated transcriptional regulation, anabolic signaling pathways, and potential differences in pharmacokinetic behavior compared with related investigational compounds.

Observed biological activities in research

• Limited publicly available experimental data
• Investigation as an androgen receptor modulator
• Evaluation in exploratory pharmacological research

Reported molecular mechanisms

• Putative androgen receptor modulation
• Nuclear receptor signaling (theoretical based on compound class)
• Mechanistic profile not fully characterized

Physiological pathways involved

• Androgen receptor signaling
• Gene transcription regulated by androgen receptor activation
• Skeletal muscle biology (under investigation)
• Bone physiology (under investigation)

Experimental outcomes in models

• Limited peer-reviewed experimental evidence available
• Biological effects remain under investigation
• Pharmacological profile not fully established

Current evidence remains limited, and further well-controlled clinical studies are required to establish long-term efficacy and safety in humans.

Research Data Sheet 

The following summarizes the currently available research specifications for RAD-150.

• Compound / Peptide Name: RAD-150
• Sequence: Not applicable
• Classification: Synthetic investigational androgen receptor modulator
• Molecular Formula: C₁₆H₂₅ClN₂O
• CAS Number: Not available
• Form: tablet
• Purity: 99% (manufacturer specification)
• Solubility: Research-dependent
• Research Categories: Androgen Receptor Biology; Nuclear Receptor Signaling; Skeletal Muscle Biology; Bone Biology; Pharmacology; Medicinal Chemistry

Safety Precautions 

RAD-150 should be handled exclusively as an investigational laboratory research compound by trained personnel operating under appropriate laboratory safety procedures. Laboratory handling should comply with institutional safety guidelines, including appropriate storage, documentation, labeling, and disposal procedures to maintain research integrity and regulatory compliance.

• Research use only
• Not for human consumption
• Not intended to diagnose, treat, or prevent disease
• Wear appropriate PPE, including gloves, laboratory coat, and eye protection
• Use aseptic handling techniques where appropriate
• Store according to manufacturer recommendations
• Avoid repeated freeze–thaw cycles where applicable
• Maintain proper labeling and laboratory documentation
• Dispose of waste according to institutional and regulatory requirements
• Human safety data remain limited
• Potential long-term biological effects have not been fully characterized

Conclusion 

RAD-150 is an investigational androgen receptor modulator that has generated interest because of its structural relationship to other compounds within the SARM class. Current research focuses primarily on understanding androgen receptor signaling, tissue-selective receptor modulation, and potential differences in biological activity compared with structurally related investigational compounds.

Given the limited amount of published experimental and clinical data, RAD-150 should be regarded as an exploratory research compound whose biological properties require further investigation through rigorous in vitro, preclinical, and clinical studies. Its principal value currently lies in supporting laboratory investigations of androgen receptor pharmacology, medicinal chemistry, and nuclear receptor signaling rather than established biomedical applications.