SELANK 10mg

Description

Selank is a synthetic heptapeptide developed as an analogue of the naturally occurring immunomodulatory peptide tuftsin. It consists of seven amino acids (Thr-Lys-Pro-Arg-Pro-Gly-Pro) and has been extensively investigated in experimental neuroscience and neuroimmunology research.

Although Selank has been studied in both preclinical models and limited human clinical studies (primarily in Russia), it is not approved by major regulatory agencies such as the FDA or EMA for therapeutic use. Current scientific interest focuses on its potential effects on neurotransmission, stress physiology, neuroimmune interactions, and cognitive function.

Specifications 

• Peptide: Selank
• Classification: Synthetic heptapeptide
• Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro
• Form: Lyophilized peptide powder
• Strength: 10 mg per vial
• Purity: ≥98% (batch dependent)
• Regulatory Status: Research-grade peptide intended for laboratory research only

What Is It Used For and Its Purpose 

Selank is primarily used as a research compound to investigate biological pathways involved in the central nervous system and immune system. Rather than acting through a single receptor, available evidence suggests that Selank may influence several interconnected molecular pathways involved in stress adaptation and neural regulation. Researchers utilize Selank to better understand mechanisms involved in neurochemical signaling, behavioral responses, and neuroimmune communication.

Common Research Applications 

• Investigation of GABAergic neurotransmission and inhibitory neural signaling
• Research on serotonin, dopaminergic, and noradrenergic neurotransmitter systems
• Studies of stress-response mechanisms and anxiety-related behavior in animal models
• Investigation of learning, memory formation, and cognitive performance
• Research into neuroplasticity and neuronal adaptation
• Evaluation of brain-derived neurotrophic factor (BDNF) expression in experimental models
• Investigation of cytokine regulation and neuroimmune interactions
• Studies examining gene expression related to neural and immune function
• Behavioural neuroscience and experimental psychopharmacology research
• Experimental models of stress resilience and adaptation

Potential Scientific Benefits 

Published experimental studies suggest that Selank exhibits a broad range of biological activities affecting both neurological and immunological systems. However, most evidence comes from preclinical studies, and larger well-controlled clinical trials are required to confirm these findings in humans. Current literature suggests that Selank may influence neurotransmitter balance, gene expression, neuroplasticity, and immune signaling, making it an important molecule for mechanistic research rather than an established therapeutic agent.

Potential Biological Effects Reported in Research 

• Modulation of GABAergic neurotransmission, which may contribute to stress-response regulation
• Influence on serotonin, dopamine, and norepinephrine signaling pathways
• Investigation of anxiolytic-like effects in preclinical and limited clinical studies
• Potential modulation of BDNF expression associated with neuronal plasticity
• Investigation of learning, memory consolidation, and cognitive processing
• Evaluation of attention and information processing in behavioural studies
• Research into neuroprotective mechanisms in cellular and animal models
• Modulation of cytokine production and neuroimmune signaling
• Investigation of adaptive responses to physiological and psychological stress
• Studies examining changes in gene expression involved in neural and immune regulation

Scientific Note: Current evidence does not conclusively demonstrate that Selank improves cognition, treats anxiety, or provides neuroprotection in humans. These remain active areas of scientific investigation.

Research Data Sheet 

Selank is a well-characterized research peptide with established physicochemical properties that support laboratory investigations in neuroscience and neuroimmunology.

• Peptide: Selank
• Classification: Synthetic Heptapeptide
• Strength: 10mg per vial
• Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro
• Molecular Formula: C₃₃H₅₇N₁₁O₉
• Molecular Weight: 751.9 g/mol
• CAS Number: 129954-34-3
• PubChem CID: 11765600
• ChemSpider ID: 9940290
• ChEMBL ID: CHEMBL4297607
• Form: Lyophilized peptide powder
• Appearance: White to off-white
• Purity: ≥98% (batch dependent)
• Solubility: Soluble in sterile or bacteriostatic water for research preparation
• Storage: 2–8°C refrigerated before reconstitution; -20°C or below for long-term storage
• Research Category: Neuroscience, Neuroimmunology, Cognitive Science, Stress Physiology

Safety Precautions 

Selank should be handled according to standard laboratory safety procedures. As a research peptide, it is intended exclusively for scientific investigation by qualified personnel. There is currently insufficient evidence regarding long-term safety in humans, and the peptide has not received approval for routine clinical or veterinary use in most jurisdictions.

• For laboratory research use only
• Not approved for human or veterinary administration in most jurisdictions
• Not intended to diagnose, treat, cure, or prevent any disease
• Wear appropriate laboratory PPE, including gloves, eye protection, and laboratory coat
• Maintain aseptic technique during preparation and handling
• Store according to recommended temperature conditions
• Avoid repeated freeze–thaw cycles following reconstitution
• Label all prepared solutions with concentration and preparation date
• Dispose of unused material according to institutional laboratory safety procedures
• Consider potential interactions when used in studies involving GABAergic or monoaminergic compounds
• Long-term human safety, pharmacokinetics, and efficacy remain incompletely characterized

Conclusion 

Selank is a synthetic heptapeptide that has attracted considerable scientific interest because of its potential interactions with multiple neurobiological and immunological pathways. Experimental research suggests that it may influence neurotransmitter systems, stress-response mechanisms, neuroimmune communication, and gene expression, making it a valuable tool for laboratory investigations into brain function and adaptive physiology.

While preclinical studies and limited clinical investigations have reported promising biological activity, the current body of evidence is insufficient to establish Selank as a proven therapeutic agent. Additional high-quality, randomized clinical trials are required to better define its mechanisms of action, efficacy, and long-term safety.