Epitalon – 50mg

Description

Epitalon is a synthetic tetrapeptide consisting of four amino acids and is a research compound investigated primarily within the fields of endocrinology, molecular aging biology, circadian regulation, and cellular physiology. It was originally developed as a synthetic analog related to peptide extracts studied from the pineal gland, particularly research surrounding pineal-derived regulatory factors and their influence on biological rhythms.

The reported sequence of Epitalon is Ala-Glu-Asp-Gly (AEDG). Experimental studies have investigated its potential relationship with pineal gland activity, melatonin regulation, antioxidant pathways, and cellular aging mechanisms. Proposed mechanisms include modulation of gene expression involved in circadian biology and possible interactions with pathways associated with telomere maintenance.

Preclinical research has explored Epitalon’s effects in cellular models, including investigations into oxidative stress responses, endocrine regulation, immune function, and age-associated biological processes. Some studies have reported changes in telomerase activity and antioxidant enzyme expression, although the relevance of these findings to human aging biology remains uncertain.

Product Specifications

• Peptide Name: Epitalon (Epithalon)
• Classification: Synthetic tetrapeptide / pineal-derived peptide analog
• Sequence: Ala-Glu-Asp-Gly (AEDG)
• Molecular Formula: C₁₄H₂₅N₅O₉ (reported in scientific literature; verification recommended for specific product batch)
• Molecular Weight: 395.37 g/mol (reported)
• CAS Number: 307297-39-8 (commonly reported)
• Form: Lyophilized peptide powder
• Strength: 50 mg
• Appearance: Typically a white to off-white lyophilized powder
• Storage: Store according to supplier recommendations; commonly stored under refrigerated or frozen conditions
• Solubility: Research-dependent
• Regulatory Status: Research compound; not approved as a therapeutic drug

What Is It Used For and Its Purpose 

Epitalon is primarily studied as a research peptide in the fields of aging biology, endocrine regulation, and circadian physiology. Researchers investigate its potential influence on biological systems associated with the pineal gland, including melatonin-related signaling and regulation of cellular responses to oxidative stress.

In molecular biology studies, Epitalon has been examined for possible effects on gene expression, antioxidant defense mechanisms, and telomere-associated processes. Experimental findings have suggested potential interactions with pathways involved in cellular longevity. The peptide is also investigated as a model compound for understanding how short regulatory peptides may influence complex physiological networks involving endocrine signaling, cellular stress responses, and age-associated molecular pathways.

Research Applications

• Aging biology research
• Endocrinology
• Circadian biology
• Pineal gland signaling research
• Oxidative stress research
• Telomere biology
• Cellular senescence research
• Molecular longevity pathways
• Gene expression studies

Potential Scientific Benefits 

Research into Epitalon has focused on its potential biological effects related to cellular aging, circadian regulation, and antioxidant responses. In vitro and animal studies have reported alterations in markers associated with oxidative stress regulation, cellular protection pathways, and endocrine signaling.

Some investigations have examined Epitalon’s relationship with telomerase activity and telomere maintenance mechanisms. These findings have generated interest in the peptide as a research tool for studying molecular processes associated with cellular lifespan. Studies have investigated possible effects on immune function, metabolic regulation, and age-associated physiological changes.

Potential biological activities reported in research include:

• Modulation of antioxidant defense pathways
• Alterations in expression of selected aging-associated molecular markers
• Investigation of telomerase and telomere-related mechanisms
• Influence on pineal-related endocrine signaling
• Potential interaction with circadian regulatory pathways
• Changes in cellular stress response markers in experimental models

Reported molecular mechanisms

• Possible regulation of gene expression involved in cellular stress responses
• Investigation of antioxidant enzyme activity modulation
• Potential influence on telomere-associated pathways
• Possible interaction with circadian and endocrine regulatory systems

Physiological pathways involved

• Pineal gland signaling
• Melatonin-associated regulation
• Oxidative stress response pathways
• Cellular aging pathways
• Endocrine signaling networks

Experimental outcomes in models

• Changes in oxidative stress markers
• Alterations in selected gene expression profiles
• Reported effects on telomere-associated measurements in some studies
• Observed physiological changes in animal research models

Current evidence remains limited, and further well-controlled clinical studies are required to determine the long-term biological effects, efficacy, and safety profile of Epitalon in humans.

Research Data Sheet 

• Compound / Peptide Name: Epitalon (Epithalon)
• Sequence: Ala-Glu-Asp-Gly (AEDG)
• Classification: Synthetic tetrapeptide
• Molecular Formula: C₁₄H₂₅N₅O₉
• Molecular Weight: 395.37 g/mol
• CAS Number: 307297-39-8
• Form: Lyophilized peptide powder
• Appearance: White to off-white powder (typical peptide appearance)
• Storage: Store according to supplier specifications; commonly refrigerated or frozen
• Research Categories: Aging Biology, Endocrinology, Circadian Biology, Oxidative Stress Research, Telomere Biology, Molecular Biology

Safety Precautions 

Epitalon is supplied strictly as a research compound and should only be handled by qualified laboratory personnel using appropriate laboratory safety procedures. Laboratory handling should follow standard peptide research practices, including appropriate storage, contamination control, documentation, and disposal procedures.

• Research use only
• Not for human consumption
• Not intended to diagnose, treat, or prevent disease
• Wear appropriate PPE including gloves, laboratory coat, and eye protection
• Maintain aseptic handling procedures during preparation and experimentation
• Store under recommended temperature conditions
• Avoid repeated freeze–thaw cycles
• Ensure proper labeling and documentation
• Dispose of waste according to institutional and regulatory requirements
• Limited human safety data are available
• Potential unknown long-term biological effects remain under investigation

Conclusion 

Epitalon is a synthetic tetrapeptide studied as a research compound in molecular aging, endocrine biology, and circadian regulation. Its small peptide structure and reported relationship to pineal-derived regulatory peptides have made it a subject of investigation in studies examining cellular stress responses and age-associated biological pathways. Reported findings suggest possible influences on antioxidant mechanisms, gene regulation, telomere-associated processes, and endocrine signaling; however, these findings remain preliminary and do not establish clinical applications.

Epitalon continues to be investigated as a tool for understanding complex biological processes involved in cellular aging and physiological regulation. Additional rigorous research is needed to clarify its molecular targets, biological effects, pharmacological properties, and safety profile.